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The endometrium as a source of mesenchymal stem cells for regenerative medicine.

ABSTRACT: Stem cell therapies have opened new frontiers in medicine with the possibility of regenerating lost or damaged cells. Embryonic stem cells, induced pluripotent stem cells, hematopoietic stem cells, and mesenchymal stem cells have been used to derive mature cell types for tissue regeneration and repair. However, the endometrium has emerged as an attractive, novel source of adult stem cells that are easily accessed and demonstrate remarkable differentiation capacity. In this review, we summarize our current understanding of endometrial stem cells and their therapeutic potential in regenerative medicine.

SUBMITTER: Mutlu L

PROVIDER: S-EPMC4652610 | biostudies-other | 2015 Jun

REPOSITORIES: biostudies-other

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The endometrium as a source of mesenchymal stem cells for regenerative medicine.

Mutlu Levent L Hufnagel Demetra D Taylor Hugh S HS

Biology of reproduction 20150422 6

Stem cell therapies have opened new frontiers in medicine with the possibility of regenerating lost or damaged cells. Embryonic stem cells, induced pluripotent stem cells, hematopoietic stem cells, and mesenchymal stem cells have been used to derive mature cell types for tissue regeneration and repair. However, the endometrium has emerged as an attractive, novel source of adult stem cells that are easily accessed and demonstrate remarkable differentiation capacity. In this review, we summarize o ...[more]

PMID: 25904012

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