Ontology highlight
ABSTRACT:
SUBMITTER: Vallejo M
PROVIDER: S-EPMC46576 | biostudies-other | 1993 May
REPOSITORIES: biostudies-other
Vallejo M M Ron D D Miller C P CP Habener J F JF
Proceedings of the National Academy of Sciences of the United States of America 19930501 10
Members of the C/EBP family of basic-leucine zipper (bZip) transcription factors form heterodimers and bind to the CAAT box and other sequence-related enhancer motifs. Using a 32P-labeled protein probe consisting of the bZip domain of C/EBP beta, we isolated a clone encoding C/EBP-related ATF (C/ATF), a bZip protein that heterodimerizes with C/EBP-like proteins but belongs to the CREB/ATF family. C/ATF homodimers do not bind to typical C/EBP DNA sites. Instead they bind to palindromic cAMP respo ...[more]