Spatial Organization of Epigenomes.
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ABSTRACT:
SUBMITTER: Dube JC
PROVIDER: S-EPMC4723270 | biostudies-other | 2016 Mar
REPOSITORIES: biostudies-other
Publications
Spatial Organization of Epigenomes.
Dubé Jonathan Christopher JC Wang Xue Qing David XQ Dostie Josée J
Current molecular biology reports 20160204 1
The role of genome architecture in transcription regulation has become the focus of an increasing number of studies over the past decade. Chromatin organization can have a significant impact on gene expression by promoting or restricting the physical proximity between regulatory DNA elements. Given that any change in chromatin state has the potential to alter DNA folding and the proximity between control elements, the spatial organization of chromatin is inherently linked to its molecular compos ...[more]
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