Ontology highlight
ABSTRACT:
SUBMITTER: Kimball BA
PROVIDER: S-EPMC4725859 | biostudies-other | 2016 Jan
REPOSITORIES: biostudies-other
Kimball Bruce A BA Wilson Donald A DA Wesson Daniel W DW
Scientific reports 20160114
In the present study, we tested whether the volatile metabolome was altered by mutations of the Alzheimer's disease (AD)-implicated amyloid precursor protein gene (APP) and comprehensively examined urinary volatiles that may potentially serve as candidate biomarkers of AD. Establishing additional biomarkers in screening populations for AD will provide enhanced diagnostic specificity and will be critical in evaluating disease-modifying therapies. Having strong evidence of gross changes in the vol ...[more]