Ontology highlight
ABSTRACT:
SUBMITTER: Markovich D
PROVIDER: S-EPMC47290 | biostudies-other | 1993 Sep
REPOSITORIES: biostudies-other
Markovich D D Forgo J J Stange G G Biber J J Murer H H
Proceedings of the National Academy of Sciences of the United States of America 19930901 17
Injection of rat kidney cortex mRNA into Xenopus laevis oocytes leads to a stimulation of Na(+)-dependent SO4(2-) uptake. Based on this information, we have isolated from a corresponding library a cDNA (NaSi-1) that is most likely related to a Na+/SO4(2-) cotransport system. NaSi-1 cRNA leads in a time- and dose-dependent manner to specific stimulation of Na(+)-dependent SO4(2-) uptake in oocytes. The apparent affinity constants of the NaSi-1 cRNA-expressed transport resemble those of Na+/SO4(2- ...[more]