Ontology highlight
ABSTRACT:
SUBMITTER: Ishii K
PROVIDER: S-EPMC4744701 | biostudies-other | 2015 Oct
REPOSITORIES: biostudies-other
Stem cells (Dayton, Ohio) 20150628 10
Satellite cells are maintained in an undifferentiated quiescent state, but during muscle regeneration they acquire an activated stage, and initiate to proliferate and differentiate as myoblasts. The transmembrane protein teneurin-4 (Ten-4) is specifically expressed in the quiescent satellite cells; however, its cellular and molecular functions remain unknown. We therefore aimed to elucidate the function of Ten-4 in muscle satellite cells. In the tibialis anterior (TA) muscle of Ten-4-deficient m ...[more]