Ontology highlight
ABSTRACT:
SUBMITTER: Alvarado-Luna G
PROVIDER: S-EPMC4758961 | biostudies-other | 2016 Feb
REPOSITORIES: biostudies-other
Alvarado-Luna Gabriela G Morales-Espinosa Daniela D
Translational lung cancer research 20160201 1
Small cell lung cancer (SCLC) represents between 13% and 15% of all diagnosed lung cancers worldwide. It is an aggressive neoplasia, with a 5-year mortality of 90% or more. It has historically been classified as limited disease (LD) and extensive disease (ED) in most study protocols. The cornerstone of treatment for any stage of SCLC is etoposide-platinum based chemotherapy; in limited stage (LS), concomitant radiotherapy to thorax and mediastinum. Prophylactic radiotherapy to the central nervou ...[more]