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Cancer cell associated glycans as targets for immunotherapy.


ABSTRACT: Therapeutic anti-glycan antibodies for cancer treatment are limited, in spite of the differential glycophenotype of cancer cells and associated biology. We have generated anti-Le glycan antibodies with clinical potential and multifaceted functionality. Increased understanding of all aspects of glycomic research will ensure the continued development of glycan-targeted immunotherapeutics.

SUBMITTER: Vankemmelbeke M 

PROVIDER: S-EPMC4760334 | biostudies-other | 2016

REPOSITORIES: biostudies-other

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