Targets for immunotherapy of liver cancer.
Ontology highlight
ABSTRACT:
SUBMITTER: Greten TF
PROVIDER: S-EPMC5857416 | biostudies-literature | 2017 Sep
REPOSITORIES: biostudies-literature
Publications
Targets for immunotherapy of liver cancer.
Greten Tim F TF Sangro Bruno B
Journal of hepatology 20170918
Drug development in hepatocellular carcinoma (HCC) has been characterised by many failures in the past. Despite good rationales and promising phase II data, many phase III trials failed. Immunotherapy represents an alternative treatment approach that has been successful in many different cancer types. As an inflammation induced cancer, HCC represents a very interesting target for immune based approaches. Indeed, early results from clinical trials testing immune checkpoint inhibitors are not only ...[more]
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