Ontology highlight
ABSTRACT:
SUBMITTER: Paschen M
PROVIDER: S-EPMC4761884 | biostudies-other | 2016 Feb
REPOSITORIES: biostudies-other
Paschen Meike M Moede Tilo T Leibiger Barbara B Jacob Stefan S Bryzgalova Galyna G Leibiger Ingo B IB Berggren Per-Olof PO
Scientific reports 20160222
Insulin resistance contributes to the development of cardio-vascular disease and diabetes. An important but unresolved task is to study the dynamics of insulin resistance in selective cell types of insulin target tissues in vivo. Here we present a novel technique to monitor insulin resistance dynamics non-invasively and longitudinally in vivo in a cell type-specific manner, exemplified by the pancreatic β-cell situated within the micro-organ the islet of Langerhans. We utilize the anterior chamb ...[more]