Ontology highlight
ABSTRACT:
SUBMITTER: Garfin PM
PROVIDER: S-EPMC4767252 | biostudies-other | 2016
REPOSITORIES: biostudies-other
Garfin Phillip M PM Nguyen Thuyen T Sage Julien J
PloS one 20160225 2
The thymus is the site of T cell development and selection. In addition to lymphocytes, the thymus is composed of several types of stromal cells that are exquisitely organized to create the appropriate environment and microenvironment to support the development and selection of maturing T cells. Thymic epithelial cells (TECs) are one of the more important cell types in the thymic stroma, and they play a critical role in selecting functional T cell clones and supporting their development. In this ...[more]