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Transient monosomy 7 in a chronic myelogenous leukemia patient during nilotinib therapy: a case report.


ABSTRACT: Tyrosine kinase inhibitor treated chronic myelogenous leukemia patients with monosomy 7 arising in Philadelphia chromosome negative (Ph-) cells tend to evolve into MDS/AML. However, monosomy 7 in Ph- cells can be a transient finding, and it is not an absolute indication of the emergence of a new myeloid malignancy.

SUBMITTER: Jawad MD 

PROVIDER: S-EPMC4771850 | biostudies-other | 2016 Mar

REPOSITORIES: biostudies-other

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