Ontology highlight
ABSTRACT:
SUBMITTER: Zheng X
PROVIDER: S-EPMC4827083 | biostudies-other | 2016 Apr
REPOSITORIES: biostudies-other
Zheng Xiaojiao X Chen Tianlu T Zhao Aihua A Wang Xiaoyan X Xie Guoxiang G Huang Fengjie F Liu Jiajian J Zhao Qing Q Wang Shouli S Wang Chongchong C Zhou Mingmei M Panee Jun J He Zhigang Z Jia Wei W
Scientific reports 20160411
Comprehensive and accurate characterization of brain metabolome is fundamental to brain science, but has been hindered by technical limitations. We profiled the brain metabolome in male Wistar rats at different ages (day 1 to week 111) using high-sensitivity and high-resolution mass spectrometry. Totally 380 metabolites were identified and 232 of them were quantitated. Compared with anatomical regions, age had a greater effect on variations in the brain metabolome. Lipids, fatty acids and amino ...[more]