Ontology highlight
ABSTRACT:
SUBMITTER: Papmeyer M
PROVIDER: S-EPMC4834463 | biostudies-other | 2016 Feb
REPOSITORIES: biostudies-other
Papmeyer Martina M Sussmann Jessika E JE Stewart Tiffany T Giles Stephen S Centola John G JG Zannias Vasileios V Lawrie Stephen M SM Whalley Heather C HC McIntosh Andrew M AM
Psychiatry research. Neuroimaging 20151231
Subcortical volumetric brain abnormalities have been observed in mood disorders. However, it is unknown whether these reflect adverse effects predisposing to mood disorders or emerge at illness onset. Magnetic resonance imaging was conducted at baseline and after two years in 111 initially unaffected young adults at increased risk of mood disorders because of a close family history of bipolar disorder and 93 healthy controls (HC). During the follow-up, 20 high-risk subjects developed major depre ...[more]