Ontology highlight
ABSTRACT:
SUBMITTER: Wang G
PROVIDER: S-EPMC4865803 | biostudies-other | 2016
REPOSITORIES: biostudies-other
Wang Guan G Zhang Liang L Chen Xingxing X Xue Xin X Guo Qiaonan Q Liu Mingyong M Zhao Jianhua J
Scientific reports 20160513
Neural stem cells (NSCs) bear characteristics for proliferation, migration and differentiation into three main neural cell type(s): neurons, astrocytes and/or oligodendrocytes. Formylpeptide receptors (Fprs), belonging to the family of G protein-coupled chemoattractant receptors, have been detected on neurons in the central nervous system (CNS). Here, we report that Fpr1 and Fpr2 are expressed on NSCs as detected with immunohistochemistry, RT-PCR and WB assays. In addition, Fpr1 and Fpr2 promote ...[more]