Ontology highlight
ABSTRACT:
SUBMITTER: Feiner R
PROVIDER: S-EPMC4900449 | biostudies-other | 2016 Jun
REPOSITORIES: biostudies-other
Feiner Ron R Engel Leeya L Fleischer Sharon S Malki Maayan M Gal Idan I Shapira Assaf A Shacham-Diamand Yosi Y Dvir Tal T
Nature materials 20160314 6
In cardiac tissue engineering approaches to treat myocardial infarction, cardiac cells are seeded within three-dimensional porous scaffolds to create functional cardiac patches. However, current cardiac patches do not allow for online monitoring and reporting of engineered-tissue performance, and do not interfere to deliver signals for patch activation or to enable its integration with the host. Here, we report an engineered cardiac patch that integrates cardiac cells with flexible, freestanding ...[more]