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Porcine cancer models for translational oncology.


ABSTRACT: Large-animal cancer models are needed to advance the development of innovative and clinically applicable tumor diagnostic, therapeutic, and monitoring technologies. We developed a genetically modified porcine model of cancer based on a TP53 mutation, and established its utility for tracking tumorigenesis in vivo through non-invasive clinical imaging approaches.

SUBMITTER: Sieren JC 

PROVIDER: S-EPMC4905218 | biostudies-other | 2014 Oct-Dec

REPOSITORIES: biostudies-other

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