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Induction of pyroptosis in colon cancer cells by LXRβ.


ABSTRACT: Liver X receptors (LXRs) have been proposed to have some anticancer properties. We recently identified a new non-genomic role of LXRβ in colon cancer cells. Under LXR agonist treatment, LXRβ induces pyroptosis of these cells in vitro and in vivo, raising the possibility of targeting this isoform in cancer treatment.

SUBMITTER: Rebe C 

PROVIDER: S-EPMC4905240 | biostudies-other | 2015 Jan-Mar

REPOSITORIES: biostudies-other

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