Unknown

Dataset Information

0

Redefining the roles of apoptotic factors in carcinogenesis.


ABSTRACT: In a recent study we reported that mammalian cells exposed to stress such as ionizing radiation can survive with activation of caspase-3 or caspase-7. We found that sublethal activation of the executioner caspases promotes chemical- and radiation-induced genetic instability and carcinogenesis, in contrast to their perceived roles as tumor suppressors.

SUBMITTER: Liu X 

PROVIDER: S-EPMC4909400 | biostudies-other | 2016 May

REPOSITORIES: biostudies-other

Similar Datasets

| S-EPMC6108115 | biostudies-literature
| S-EPMC6495773 | biostudies-literature
| S-EPMC6977632 | biostudies-literature
| S-EPMC7479936 | biostudies-literature
| S-EPMC6584882 | biostudies-literature
| S-EPMC3058916 | biostudies-literature
| S-EPMC5288315 | biostudies-literature
| S-EPMC6856719 | biostudies-literature
| S-EPMC5399169 | biostudies-literature
| S-EPMC8333267 | biostudies-literature