Roles of FGFR in oral carcinogenesis.
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ABSTRACT:
SUBMITTER: Xie X
PROVIDER: S-EPMC6495773 | biostudies-literature | 2016 Jun
REPOSITORIES: biostudies-literature
Publications
Roles of FGFR in oral carcinogenesis.
Xie Xiaoyan X Wang Zhiyong Z Chen Fangman F Yuan Yao Y Wang Jiayi J Liu Rui R Chen Qianming Q
Cell proliferation 20160601 3
Fibroblast growth factor receptors (FGFRs) play essential roles in organ development during the embryonic period, and regulate tissue repair in adults. Accumulating evidence suggests that alterations in FGFR signalling are involved in diverse types of cancer. In this review, we focus on aberrant regulation of FGFRs in pathogenesis of oral squamous cell carcinoma (OSCC), including altered expression and subcellular location, aberrant isoform splicing and mutations. We also provide an overview of ...[more]
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