Competing endogenous RNA networks in human cancer: hypothesis, validation, and perspectives.
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ABSTRACT:
SUBMITTER: Yang C
PROVIDER: S-EPMC4924655 | biostudies-other | 2016 Mar
REPOSITORIES: biostudies-other
Publications
Competing endogenous RNA networks in human cancer: hypothesis, validation, and perspectives.
Yang Chao C Wu Di D Gao Lin L Liu Xi X Jin Yinji Y Wang Dong D Wang Tianzhen T Li Xiaobo X
Oncotarget 20160301 12
Non-coding RNAs represent a majority of the human transcriptome. However, less is known about the functions and regulatory mechanisms of most non-coding species. Moreover, little is known about the potential non-coding functions of coding RNAs. The competing endogenous RNAs (ceRNAs) hypothesis is proposed recently. This hypothesis describes potential communication networks among all transcript RNA species mediated by miRNAs and miRNA-recognizing elements (MREs) within RNA transcripts. Here we re ...[more]
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