Ontology highlight
ABSTRACT:
SUBMITTER: Yang S
PROVIDER: S-EPMC4967827 | biostudies-other | 2016 Jul
REPOSITORIES: biostudies-other
Yang Shaoyuan S Pei Hairun H Zhang Xiaoying X Wei Qiang Q Zhu Jia J Zheng Jimin J Jia Zongchao Z
Open biology 20160701 7
DicB, a protein encoded by the Kim (Qin) prophage in Escherichia coli, inhibits cell division through interaction with MinC. Thus far, characterization of DicB has been severely hampered owing to its potent activity which ceases cell division and leads to cell death. In this work, through fusing maltose-binding protein to the N-terminus of DicB (MBP-DicB), we successfully expressed and purified recombinant DicB that enabled in vitro analysis for the first time. More importantly, taking advantage ...[more]