Cytotoxic T lymphocyte antigen-4 expression in esophageal carcinoma: implications for prognosis.
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ABSTRACT:
SUBMITTER: Zhang XF
PROVIDER: S-EPMC5042006 | biostudies-other | 2016 May
REPOSITORIES: biostudies-other
Publications
Cytotoxic T lymphocyte antigen-4 expression in esophageal carcinoma: implications for prognosis.
Zhang Xiao-Fei XF Pan Ke K Weng De-Sheng DS Chen Chang-Long CL Wang Qi-Jing QJ Zhao Jing-Jing JJ Pan Qiu-Zhong QZ Liu Qing Q Jiang Shan-Shan SS Li Yong-Qiang YQ Zhang Hong-Xia HX Xia Jian-Chuan JC
Oncotarget 20160501 18
To examine the relationship between cytotoxic T lymphocyte antigen-4 (CTLA-4) expression and esophageal carcinoma prognosis, CTLA-4 expression was immunohistochemically detected in paraffin-embedded primary tumor specimens from 158 patients with esophageal cancer. CTLA-4 was detected in the cytoplasm and cell membranes of esophageal cancer cells and in interstitial lymphocytes. In univariate analyses (log-rank), higher interstitial CTLA-4+ lymphocyte density and higher tumor CTLA-4 expression we ...[more]
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