Ontology highlight
ABSTRACT:
SUBMITTER: Lu CL
PROVIDER: S-EPMC5126967 | biostudies-other | 2016 May
REPOSITORIES: biostudies-other
Lu Ching-Lan CL Murakowski Dariusz K DK Bournazos Stylianos S Schoofs Till T Sarkar Debolina D Halper-Stromberg Ariel A Horwitz Joshua A JA Nogueira Lilian L Golijanin Jovana J Gazumyan Anna A Ravetch Jeffrey V JV Caskey Marina M Chakraborty Arup K AK Nussenzweig Michel C MC
Science (New York, N.Y.) 20160505 6288
Antiretroviral drugs and antibodies limit HIV-1 infection by interfering with the viral life cycle. In addition, antibodies also have the potential to guide host immune effector cells to kill HIV-1-infected cells. Examination of the kinetics of HIV-1 suppression in infected individuals by passively administered 3BNC117, a broadly neutralizing antibody, suggested that the effects of the antibody are not limited to free viral clearance and blocking new infection but also include acceleration of in ...[more]