Programmed necrosis - a new mechanism of steroidogenic luteal cell death and elimination during luteolysis in cows.
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ABSTRACT:
SUBMITTER: Hojo T
PROVIDER: S-EPMC5128806 | biostudies-other | 2016 Nov
REPOSITORIES: biostudies-other
Publications
Programmed necrosis - a new mechanism of steroidogenic luteal cell death and elimination during luteolysis in cows.
Hojo Takuo T Siemieniuch Marta J MJ Lukasik Karolina K Piotrowska-Tomala Katarzyna K KK Jonczyk Agnieszka W AW Okuda Kiyoshi K Skarzynski Dariusz J DJ
Scientific reports 20161130
Programmed necrosis (necroptosis) is an alternative form of programmed cell death that is regulated by receptor-interacting protein kinase (RIPK) 1 and 3-dependent, but is a caspase (CASP)-independent pathway. In the present study, to determine if necroptosis participates in bovine structural luteolysis, we investigated RIPK1 and RIPK3 expression throughout the estrous cycle, during prostaglandin F2α (PGF)-induced luteolysis in the bovine corpus luteum (CL), and in cultured luteal steroidogenic ...[more]
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