Ontology highlight
ABSTRACT:
SUBMITTER: Ichimura T
PROVIDER: S-EPMC5155549 | biostudies-other | 2015 Jun
REPOSITORIES: biostudies-other
Ichimura Taro T Chiu Liang-da LD Fujita Katsumasa K Machiyama Hiroaki H Kawata Satoshi S Watanabe Tomonobu M TM Fujita Hideaki H
Scientific reports 20150616
Using Raman spectral imaging, we visualized the cell state transition during differentiation and constructed hypothetical potential landscapes for attractors of cellular states on a state space composed of parameters related to the shape of the Raman spectra. As models of differentiation, we used the myogenic C2C12 cell line and mouse embryonic stem cells. Raman spectral imaging can validate the amounts and locations of multiple cellular components that describe the cell state such as proteins, ...[more]