Ontology highlight
ABSTRACT:
SUBMITTER: Iwaki M
PROVIDER: S-EPMC5159853 | biostudies-other | 2016 Dec
REPOSITORIES: biostudies-other
Nature communications 20161212
Mechanosensitive biological nanomachines such as motor proteins and ion channels regulate diverse cellular behaviour. Combined optical trapping with single-molecule fluorescence imaging provides a powerful methodology to clearly characterize the mechanoresponse, structural dynamics and stability of such nanomachines. However, this system requires complicated experimental geometry, preparation and optics, and is limited by low data-acquisition efficiency. Here we develop a programmable DNA origam ...[more]