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Spontaneous mirror symmetry breaking in heterocatalytically coupled enantioselective replicators.

ABSTRACT: Chiral hypercycle replicators (first-order autocatalysis together with mutual cross-catalysis) formed from achiral or racemizing resources may lead to spontaneous mirror symmetry breaking (SMSB) without the need for additional heterochiral inhibition reactions, such as those of the Frank-like models, which are an obstacle for the emergence of evolutionary selection properties. The results indicate that the chemical models for the emergence of primordial autocatalytic self-reproducing systems, of and by themselves, can also explain naturally the emergence of biological homochirality.

SUBMITTER: Ribo JM

PROVIDER: S-EPMC5299794 | biostudies-other | 2017 Jan

REPOSITORIES: biostudies-other

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Spontaneous mirror symmetry breaking in heterocatalytically coupled enantioselective replicators.

Ribó Josep M JM Crusats Joaquim J El-Hachemi Zoubir Z Moyano Albert A Hochberg David D

Chemical science 20160913 1

Chiral hypercycle replicators (first-order autocatalysis together with mutual cross-catalysis) formed from achiral or racemizing resources may lead to spontaneous mirror symmetry breaking (SMSB) without the need for additional heterochiral inhibition reactions, such as those of the Frank-like models, which are an obstacle for the emergence of evolutionary selection properties. The results indicate that the chemical models for the emergence of primordial autocatalytic self-reproducing systems, of ...[more]

PMID: 28451224

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