A Facile and Versatile Method to Endow Biomaterial Devices with Zwitterionic Surface Coatings.
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ABSTRACT:
SUBMITTER: Yesilyurt V
PROVIDER: S-EPMC5322155 | biostudies-other | 2017 Feb
REPOSITORIES: biostudies-other
Publications
A Facile and Versatile Method to Endow Biomaterial Devices with Zwitterionic Surface Coatings.
Yesilyurt Volkan V Veiseh Omid O Doloff Joshua C JC Li Jie J Bose Suman S Xie Xi X Bader Andrew R AR Chen Michael M Webber Matthew J MJ Vegas Arturo J AJ Langer Robert R Anderson Daniel G DG
Advanced healthcare materials 20161215 4
The surface modification of implantable biomaterials with zwitterionic phosphorylcholine polymer is demonstrated through mussel-mimetic catecholamine polymer thin films. Using this method, the surfaces of alginate hydrogel microspheres and polystyrene microbeads, a model material known to produce robust foreign body responses and fibrosis, are successfully modified to reduce the tissue reaction by reducing the fibrosis in immunocompetent C57BL/6J mice. ...[more]
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