Sequential Double "Clicks" toward Structurally Well-Defined Heterogeneous N-Glycoclusters: The Importance of Cluster Heterogeneity on Pattern Recognition In Vivo.
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ABSTRACT:
SUBMITTER: Latypova L
PROVIDER: S-EPMC5323863 | biostudies-other | 2017 Feb
REPOSITORIES: biostudies-other
Publications
Sequential Double "Clicks" toward Structurally Well-Defined Heterogeneous <i>N</i>-Glycoclusters: The Importance of Cluster Heterogeneity on Pattern Recognition In Vivo.
Latypova Liliya L Sibgatullina Regina R Ogura Akihiro A Fujiki Katsumasa K Khabibrakhmanova Alsu A Tahara Tsuyoshi T Nozaki Satoshi S Urano Sayaka S Tsubokura Kazuki K Onoe Hirotaka H Watanabe Yasuyoshi Y Kurbangalieva Almira A Tanaka Katsunori K
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 20161128 2
<b>Structurally well-defined heterogeneous <i>N</i>-glycoclusters</b> are prepared on albumin via a double click procedure. The number of glycan molecules present, in addition to the spatial arrangement of glycans in the heterogeneous glycoclusters, plays an important role in the in vivo kinetics and organ-selective accumulation through glycan pattern recognition mechanisms. ...[more]
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