Ontology highlight
ABSTRACT:
SUBMITTER: Kastner P
PROVIDER: S-EPMC53758 | biostudies-other | 1990 Apr
REPOSITORIES: biostudies-other
Kastner P P Krust A A Mendelsohn C C Garnier J M JM Zelent A A Leroy P P Staub A A Chambon P P
Proceedings of the National Academy of Sciences of the United States of America 19900401 7
We have characterized seven murine retinoic acid receptor gamma cDNA isoforms (mRAR-gamma 1 to -gamma 7) generated by alternative splicing of at least seven exons. These isoforms differ from one another in their 5' untranslated region and in two cases (mRAR-gamma 1 and -gamma 2) differ in their N-terminal A region, which is known to be important for differential transactivation by other nuclear receptors. mRAR-gamma 1 and -gamma 2, the predominant isoforms, are differentially expressed in adult ...[more]