Ontology highlight
ABSTRACT:
SUBMITTER: Koike K
PROVIDER: S-EPMC54373 | biostudies-other | 1990 Aug
REPOSITORIES: biostudies-other
Proceedings of the National Academy of Sciences of the United States of America 19900801 15
A genomic clone encompassing the entire gene for the human pyruvate dehydrogenase beta subunit (PDH beta) has been isolated by screening a leukocyte genomic library with a nick-translated human foreskin fibroblast PDH beta cDNA probe. The 18-kilobase clone was characterized by restriction enzyme analysis, extensive DNA sequencing, and primer-extension analysis. The PDH beta structural gene is composed of 10 exons and 9 introns. All intron-exon splice junctions follow the GT/AG rule. The Alu fami ...[more]