Ontology highlight
ABSTRACT:
SUBMITTER: Gollnick P
PROVIDER: S-EPMC55032 | biostudies-other | 1990 Nov
REPOSITORIES: biostudies-other
Gollnick P P Ishino S S Kuroda M I MI Henner D J DJ Yanofsky C C
Proceedings of the National Academy of Sciences of the United States of America 19901101 22
We have cloned and characterized the mtr operon of Bacillus subtilis. This operon encodes a presumed RNA-binding regulatory protein that is required for attenuation control of the trp operon. We have shown that the mtr operon consists of two structural genes, mtrA and mtrB, predicted to encode 22-kDa and 8-kDa polypeptides, respectively. MtrB shows homology with RegA, an RNA-binding regulatory protein of bacteriophage T4. The lesions in several mtr mutants were localized to mtrB or the putative ...[more]