Ontology highlight
ABSTRACT:
SUBMITTER: Onutu AH
PROVIDER: S-EPMC5505372 | biostudies-other | 2015 Oct
REPOSITORIES: biostudies-other
Romanian journal of anaesthesia and intensive care 20151001 2
Serotonin and norepinephrine reuptake inhibitors are second-line antidepressants largely used because of their good tolerance and their reduced side effects. Two of these drugs, duloxetine and venlafaxine, are used also in chronic pain management. In this review we present recent data regarding duloxetine's effects on the central nervous system, linked to acute pain management, and their efficiency in reducing postoperative chronic pain. The drug's efficacy results from its modulating effect on ...[more]