Ontology highlight
ABSTRACT:
SUBMITTER: Phillips MA
PROVIDER: S-EPMC55159 | biostudies-other | 1990 Dec
REPOSITORIES: biostudies-other
Phillips M A MA Stewart B E BE Qin Q Q Chakravarty R R Floyd E E EE Jetten A M AM Rice R H RH
Proceedings of the National Academy of Sciences of the United States of America 19901201 23
The nucleotide and deduced amino acid sequences of the coding regions of human and rat keratinocyte transglutaminases (protein-glutamine: amine gamma-glutamyltransferase; EC 2.3.2.13) have been determined. These yield proteins of approximately 90 kDa that are 92% identical, indicative of the conservation of important structural features. Alignments of amino acid sequences show substantial similarity among the keratinocyte transglutaminase, human clotting factor XIII catalytic subunit, guinea pig ...[more]