Ontology highlight
ABSTRACT:
SUBMITTER: Grupe A
PROVIDER: S-EPMC551878 | biostudies-other | 1990 Jun
REPOSITORIES: biostudies-other
Grupe A A Schröter K H KH Ruppersberg J P JP Stocker M M Drewes T T Beckh S S Pongs O O
The EMBO journal 19900601 6
We have isolated and characterized a human cDNA (HBK2) that is homologous to novel member (RCK2) of the K+ channel RCK gene family expressed in rat brain. RCK2 mRNA was detected predominantly in midbrain areas and brainstem. The primary sequences of the HBK2/RCK2 K+ channel proteins exhibit major differences to other members of the RCK gene family. The bend region between segments S1 and S2 is unusually long and does not contain the N-glycosylation site commonly found in this region. They might ...[more]