Evaluation of high resolution ultrasound as a tool for assessing the 3D volume of blood clots during in vitro thrombolysis.
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ABSTRACT:
SUBMITTER: Auboire L
PROVIDER: S-EPMC5524902 | biostudies-other | 2017 Jul
REPOSITORIES: biostudies-other
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Evaluation of high resolution ultrasound as a tool for assessing the 3D volume of blood clots during in vitro thrombolysis.
Auboire Laurent L Escoffre Jean-Michel JM Fouan Damien D Jacquet Jean-René JR Ossant Frédéric F Grégoire Jean-Marc JM Bouakaz Ayache A
Scientific reports 20170724 1
Thrombosis is a major cause of several diseases, i.e. myocardial infarction, cerebral stroke and pulmonary embolism. Thrombolytic therapies are required to induce fast and efficient recanalization of occluded vessels. To evaluate the in vitro efficacy of these thrombolytic strategies, measuring clot dissolution is essential. This study aimed to evaluate and validate high resolution ultrasound as a tool to assess the exact volume of clots in 3D and in real time during in vitro thrombolytic drug t ...[more]
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