Ontology highlight
ABSTRACT:
SUBMITTER: Zhou SR
PROVIDER: S-EPMC5533882 | biostudies-other | 2017 Aug
REPOSITORIES: biostudies-other
Zhou Shui-Rong SR Guo Liang L Wang Xu X Liu Yang Y Peng Wan-Qiu WQ Liu Yuan Y Wei Xiang-Bo XB Dou Xin X Ding Meng M Lei Qun-Ying QY Qian Shu-Wen SW Li Xi X Tang Qi-Qun QQ
Molecular and cellular biology 20170728 16
White adipose tissue (WAT) serves as a reversible energy storage depot in the form of lipids in response to nutritional status. Cavin-1, an essential component in the biogenesis of caveolae, is a positive regulator of lipolysis in adipocytes. However, molecular mechanisms of cavin-1 in the modulation of lipolysis remain poorly understood. Here, we showed that cavin-1 was acetylated at lysines 291, 293, and 298 (3K), which were under nutritional regulation in WAT. We further identified GCN5 as th ...[more]