Hepatotoxicity after high-dose intravenous methylprednisolone in multiple sclerosis patients.

ABSTRACT: Hepatotoxicity is a rare adverse event of methylprednisolone that should be considered in clinical practice. In patients at risk, we propose liver function surveillance, by measuring hepatic enzymes concentration 15-30 days after methylprednisolone administration. Additionally, we propose ACTH, dexamethasone, or plasma exchange as alternate treatment options for these patients.

SUBMITTER: Hidalgo de la Cruz M 

PROVIDER: S-EPMC5538224 | biostudies-other | 2017 Aug

REPOSITORIES: biostudies-other