Ontology highlight
ABSTRACT:
SUBMITTER: Wu H
PROVIDER: S-EPMC5548895 | biostudies-other | 2017 Aug
REPOSITORIES: biostudies-other
Wu Hao H Weidinger Carl C Schmidt Franziska F Keye Jacqueline J Friedrich Marie M Yerinde Cansu C Willimsky Gerald G Qin Zhihai Z Siegmund Britta B Glauben Rainer R
Scientific reports 20170808 1
Tumor infiltrating myeloid cells play contradictory roles in the tumor development. Dendritic cells and classical activated macrophages support anti-tumor immune activity via antigen presentation and induction of pro-inflammatory immune responses. Myeloid suppressor cells (MSCs), for instance myeloid derived suppressor cells (MDSCs) or tumor associated macrophages play a critical role in tumor growth. Here, treatment with sodium oleate, an unsaturated fatty acid, induced a regulatory phenotype i ...[more]