Dataset Information

Novel Durable Antimicrobial Ceramic with Embedded Copper Sub-Microparticles for a Steady-State Release of Copper Ions.

ABSTRACT: Using pottery clay, porous ceramic stones were molded and then decorated with copper sub-microparticles inside the pores. Copper added antimicrobial functionality to the clay-based ceramic and showed ability in disinfecting water. Populations of both Staphylococcus aureus and Klebsiella pneumoniae in contaminated water were reduced by >99.9% in 3 h when exposed to an antimicrobial stone. This antimicrobial performance is attributed to a slow release of copper into water at both room and elevated temperatures. Copper is leached by water to produce ion concentrations in water at a level of 0.05-0.20 ppm after 24 to 72 h immersion tests. This concentration is reproducible over a number of cycles >400. To our knowledge, this is the first formulation of copper sub-microparticles inside the porous structure of commercial-sized ceramic stones that can disinfect bacteria-contaminated water over a period of at least several months.

SUBMITTER: Drelich AJ

PROVIDER: S-EPMC5551818 | biostudies-other | 2017 Jul

REPOSITORIES: biostudies-other

ACCESS DATA

Similar Datasets

Project description:The title hydrated copper(I)-l-cysteine-chloride complex has a polymeric structure of composition {[Cu16(CysH2)6Cl16]·xH2O} n [CysH2 = HO2CCH(NH3 +)CH2S- or C3H7NO2S], namely, poly[[tetra-μ3-chlorido-deca-μ2-chlorido-di-chlorido-hexa-kis-(μ4-l-cysteinato)hexa-deca-copper] polyhydrate]. The copper atoms are linked by thiol-ate groups to form Cu12S6 nanoclusters that take the form of a tetra-kis cubocta-hedron, made up of a Cu12 cubo-octa-hedral subunit that is augmented by six sulfur atoms that are located symmetrically atop of each of the Cu4 square units of the Cu12 cubo-octa-hedron. The six S atoms thus form an octa-hedral subunit themselves. The exterior of the Cu12S6 sphere is decorated by chloride ions and trichlorocuprate units. Three chloride ions are coordinated in an irregular fashion to trigonal Cu3 subunits of the nanocluster, and four trigonal CuCl3 units are bonded via each of their chloride ions to a copper ion on the Cu12S6 sphere. The trigonal CuCl3 units are linked via Cu2Cl2 bridges covalently connected to equivalent units in neighboring nanoclusters. Four such connections are arranged in a tetra-hedral fashion, thus creating an infinite diamond-like net of Cu12S6Cl4(CuCl3)4 nanoclusters. The network thus formed results in large channels occupied by solvent mol-ecules that are mostly too ill-defined to model. The content of the voids, believed to be water mol-ecules, was accounted for via reverse Fourier-transform methods using the SQUEEZE algorithm [Spek (2015 ▸). Acta Cryst. C71, 9-18]. The protonated amino groups of the cysteine ligands are directed away from the sphere, forming N-H⋯Cl hydrogen bonds with chloride-ion acceptors of their cluster. The protonated carb-oxy groups point outwards and presumably form O-H⋯O hydrogen bonds with the unresolved water mol-ecules of the solvent channels. Disorder is observed in one of the two crystallographically unique [Cu16(CysH2)6Cl16] segments for three of the six cysteine anions.

Dataset Information

Novel Durable Antimicrobial Ceramic with Embedded Copper Sub-Microparticles for a Steady-State Release of Copper Ions.

Similar Datasets

OmicsDI is part of the ELIXIR infrastructure