Ontology highlight
ABSTRACT:
SUBMITTER: Waseem NH
PROVIDER: S-EPMC556989 | biostudies-other | 1992 Dec
REPOSITORIES: biostudies-other
Waseem N H NH Labib K K Nurse P P Lane D P DP
The EMBO journal 19921201 13
Five monoclonal antibodies raised against rat PCNA cross-reacted with a similar protein in the fission yeast Schizosaccharomyces pombe. One of these was used to screen an S.pombe cDNA expression library. An incomplete cDNA was isolated and used to screen a genomic library, identifying a single gene, designated pcn1+ (proliferating cell nuclear antigen). The gene encodes a protein of 260 amino acids, with a deduced sequence 52% identical to human and rat PCNAs, which are 98.5% identical to each o ...[more]