Ontology highlight
ABSTRACT:
SUBMITTER: Kusche-Gullberg M
PROVIDER: S-EPMC557027 | biostudies-other | 1992 Dec
REPOSITORIES: biostudies-other
Kusche-Gullberg M M Garrison K K MacKrell A J AJ Fessler L I LI Fessler J H JH
The EMBO journal 19921201 12
A Drosophila laminin A chain gene was characterized as a 14 kb genomic nucleotide sequence which encodes an open reading frame of 3712 amino acids in 15 exons. Overall, this A chain is similar to its vertebrate counterparts, especially in its N- and C-terminal globular domains, but the sequence that forms the laminin A short arm is quite different and larger. Laminin messages appear in newly formed mesoderm and are later prominently expressed in hemocytes, which also synthesize basement membrane ...[more]