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Similarities of Variant Creutzfeldt-Jakob Disease Strain in Mother and Son in Spain to UK Reference Case.


ABSTRACT: We investigated transmission characteristics of variant Creutzfeldt-Jakob disease in a mother and son from Spain. Despite differences in patient age and disease manifestations, we found the same strain properties in these patients as in UK vCJD cases. A single strain of agent appears to be responsible for all vCJD cases to date.

SUBMITTER: Diack AB 

PROVIDER: S-EPMC5572887 | biostudies-other | 2017 Sep

REPOSITORIES: biostudies-other

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Similarities of Variant Creutzfeldt-Jakob Disease Strain in Mother and Son in Spain to UK Reference Case.

Diack Abigail B AB   Boyle Aileen A   Ritchie Diane D   Plinston Chris C   Kisielewski Dorothy D   de Pedro-Cuesta Jesús J   Rábano Alberto A   Will Robert G RG   Manson Jean C JC  

Emerging infectious diseases 20170901 9


We investigated transmission characteristics of variant Creutzfeldt-Jakob disease in a mother and son from Spain. Despite differences in patient age and disease manifestations, we found the same strain properties in these patients as in UK vCJD cases. A single strain of agent appears to be responsible for all vCJD cases to date. ...[more]

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