Ontology highlight
ABSTRACT:
SUBMITTER: Jack-Roberts C
PROVIDER: S-EPMC5579692 | biostudies-other | 2017 Aug
REPOSITORIES: biostudies-other
Jack-Roberts Chauntelle C Joselit Yaelle Y Nanobashvili Khatia K Bretter Rachel R Malysheva Olga V OV Caudill Marie A MA Saxena Anjana A Axen Kathleen K Gomaa Ahmed A Jiang Xinyin X
Nutrients 20170818 8
Maternal obesity increases fetal adiposity which may adversely affect metabolic health of the offspring. Choline regulates lipid metabolism and thus may influence adiposity. This study investigates the effect of maternal choline supplementation on fetal adiposity in a mouse model of maternal obesity. C57BL/6J mice were fed either a high-fat (HF) diet or a control (NF) diet and received either 25 mM choline supplemented (CS) or control untreated (CO) drinking water for 6 weeks before timed-mating ...[more]