Ontology highlight
ABSTRACT:
SUBMITTER: Weisman O
PROVIDER: S-EPMC5581907 | biostudies-other | 2017 Sep
REPOSITORIES: biostudies-other
Weisman Omri O Guri Yael Y Gur Raquel E RE McDonald-McGinn Donna M DM Calkins Monica E ME Tang Sunny X SX Emanuel Beverly B Zackai Elaine H EH Eliez Stephan S Schneider Maude M Schaer Marie M Kates Wendy R WR Antshel Kevin M KM Fremont Wanda W Shashi Vandana V Hooper Stephen R SR Armando Marco M Vicari Stefano S Pontillo Maria M Kushan Leila L Jalbrzikowski Maria M Bearden Carrie E CE Cubells Joseph F JF Ousley Opal Y OY Walker Elaine F EF Simon Tony J TJ Stoddard Joel J Niendam Tara A TA van den Bree Marianne B M MBM Gothelf Doron D
Schizophrenia bulletin 20170901 5
Nearly one-third of individuals with 22q11.2 deletion syndrome (22q11.2DS) develop a psychotic disorder during life, most of them by early adulthood. Importantly, a full-blown psychotic episode is usually preceded by subthreshold symptoms. In the current study, 760 participants (aged 6-55 years) with a confirmed hemizygous 22q11.2 microdeletion have been recruited through 10 medical sites worldwide, as part of an international research consortium. Of them, 692 were nonpsychotic and with complete ...[more]