Silent Sentence Completion Shows Superiority Localizing Wernicke's Area and Activation Patterns of Distinct Language Paradigms Correlate with Genomics: Prospective Study.
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ABSTRACT:
SUBMITTER: Salek KE
PROVIDER: S-EPMC5608896 | biostudies-other | 2017 Sep
REPOSITORIES: biostudies-other
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Silent Sentence Completion Shows Superiority Localizing Wernicke's Area and Activation Patterns of Distinct Language Paradigms Correlate with Genomics: Prospective Study.
Salek Kamel El KE Hassan Islam S IS Kotrotsou Aikaterini A Abrol Srishti S Faro Scott H SH Mohamed Feroze B FB Zinn Pascal O PO Wei Wei W Li Nan N Kumar Ashok J AJ Weinberg Jeffrey S JS Wefel Jeffrey S JS Kesler Shelli R SR Liu Ho-Ling Anthony HA Hou Ping P Stafford R Jason RJ Prabhu Sujit S Sawaya Raymond R Colen Rivka R RR
Scientific reports 20170921 1
Preoperative mapping of language areas using fMRI greatly depends on the paradigms used, as different tasks harness distinct capabilities to activate speech processing areas. In this study, we compared the ability of 3 covert speech paradigms: Silent Sentence Completion (SSC), category naming (CAT) and verbal fluency (FAS), in localizing the Wernicke's area and studied the association between genomic markers and functional activation. Fifteen right-handed healthy volunteers and 35 mixed-handed p ...[more]
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