Ontology highlight
ABSTRACT:
SUBMITTER: Chen L
PROVIDER: S-EPMC5622111 | biostudies-other | 2017 Sep
REPOSITORIES: biostudies-other
Scientific reports 20170929 1
The 1,3-dipolar cycloaddition of active azomethine ylide, which were generated in situ from addition reaction of α-amino acids with dialkyl acetylenedicarboxylates, with 2-arylidene-1,3-indanediones showed versatile regioselectivity and diastereoselectivity. The reaction of sarcosine and glycine afforded one kind of functionalized spiro[indene-2,3'-pyrrolidines]. The other primary α-amino acids such as alanine, phenylalanine and leucine gave another kind of regioisomeric spiro[indene-2,3'-pyrrol ...[more]