Dataset Information

Morphologic features of the distal femur and tibia plateau in Southeastern Chinese population: A cross-sectional study.

ABSTRACT: Morphologic measurements of the femoral and tibial features of western population have been done in several studies, which provides the fundamental data for the design of total knee arthroplasty prosthesis used globally, including China. However, researches on anatomic and morphologic features of the knee in Chinese populations of both sexes have never been conducted. Our study was aimed at investigating the anatomic and morphologic features of the knees of the Southeastern Chinese population by magnetic resonance imaging (MRI) scans, so as to provide parameters for sex- and ethnic-specific implant designs in the future.A total of 245 knees from 244 Chinese adults (130 females and 114 males, aging from 18 to 89 years) who received knee MRI scan from November 2014 to October 2015 were recruited and analyzed. A set of linear and angular parameters, and 6 normalized ratios were measured and calculated on the distal femur and proximal tibia.The knee size was significantly different between sexes. Compared with women, men have larger (P?

SUBMITTER: Fan L

PROVIDER: S-EPMC5704801 | biostudies-other | 2017 Nov

REPOSITORIES: biostudies-other

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Morphologic features of the distal femur and tibia plateau in Southeastern Chinese population: A cross-sectional study.

Fan Lin L Xu Tianyang T Li Xifan X Zan Pengfei P Li Guodong G

Medicine 20171101 46

Morphologic measurements of the femoral and tibial features of western population have been done in several studies, which provides the fundamental data for the design of total knee arthroplasty prosthesis used globally, including China. However, researches on anatomic and morphologic features of the knee in Chinese populations of both sexes have never been conducted. Our study was aimed at investigating the anatomic and morphologic features of the knees of the Southeastern Chinese population by ...[more]

PMID: 29145256

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Project description:BackgroundWe often attribute the lateral ankle impingement to the valgus calcaneus, while ignoring the varus distal tibia. The diagnostic criteria, severity and treatment of distal tibia varus syndrome (DTVS) have not been reported. This retrospective study sought to propose a diagnosis and classification system for DTVS based on patients' clinical symptoms and imaging findings.MethodsA total of 76 symptomatic patients with varus distal tibia and congruent ankle examined between 2010 and 2018 were involved to evaluate clinically based on their SF-36 scores, AOFAS ankle-hindfoot scores, and VAS scores. Each patient's history, symptoms, and MRI images were analyzed retrospectively, and their weight-bearing ankle radiographs were observed to measure the tibial anterior surface angle (TAS) and tibial tilt angle (TTA). Paired t-test and Kruskal-Wallis test were used to compare the results above.ResultsForty-three men and 33 women with an average age of 46 years (range, 28-68 years) included. Besides the same symptom of intermittent subfibular pain, 3 types of DTVS were defined: (I) Type I: a sloped surface of the distal tibia with the congruent tibiotalar joint on radiographs; (II) Type II: a sloped surface of the distal tibia with the congruent tibiotalar joint on radiographs, and soft-tissue edema inferior to the lateral malleolus on MRI images; and (III) Type III: the same symptoms as Type II, plus osteochondral lesions of the talus on MRI images. Under our proposed classification system, 26 patients were classified as Type I, requiring conservative treatment, 22 as Type II, and 28 as Type III under supramalleolar valgus osteotomy. The ankle functional evaluation scores, such as the SF-36 (74.14±12.50 preoperatively and 85.22±8.83 postoperatively), AOFAS (71.14±15.19 preoperatively and 87.53±8.62 postoperatively), and VAS (5.41±1.10 preoperatively and 1.82±1.08 postoperatively) scores for all types were significantly improved (P<0.01). The TAS (80.38°±4.80° preoperatively and 90.44°±3.96° postoperatively) and TTA (13.02°±3.41° preoperatively and 0.62°±2.67° postoperatively) of all the patients on the weight-bearing ankle radiographs were significantly improved (P<0.01).ConclusionsDTVS, causing lateral ankle impingement, can be diagnosed based on clinical manifestations and imaging findings. Our classification system can aid in the decision-making process in relation to the appropriate form of conservative or surgical treatments.

Project description:Computed tomography and finite element modeling were used to assess bone structure at the knee as a function of time after spinal cord injury. Analyzed regions experienced degradation in stiffness, mineral density, and content. Changes were well described as an exponential decay over time, reaching a steady state 3.5 years after injury. INTRODUCTION:Spinal cord injury (SCI) is associated with bone fragility and an increased risk of fracture around the knee. The purpose of this study was to investigate bone stiffness and mineral content at the distal femur and proximal tibia, using finite element (FE) and computed tomography (CT) measures. A cross-sectional design was used to compare differences between non-ambulatory individuals with SCI as a function of time after injury (0-50 years). METHODS:CT scans of the knee were obtained from 101 individuals who experienced an SCI 30 days to 50 years prior to participation. Subject-specific FE models were used to estimate stiffness under axial compression and torsional loading, and CT data was analyzed to assess volumetric bone mineral density (vBMD) and bone mineral content (BMC) for integral, cortical, and trabecular compartments of the epiphyseal, metaphyseal, and diaphyseal regions of the distal femur and proximal tibia. RESULTS:Bone degradation was well described as an exponential decay over time (R2?=?0.33-0.83), reaching steady-state levels within 3.6 years of SCI. Individuals at a steady state had 40 to 85% lower FE-derived bone stiffness and robust decreases in CT mineral measures, compared to individuals who were recently injured (t???47 days). Temporal and spatial patterns of bone loss were similar between the distal femur and proximal tibia. CONCLUSIONS:After SCI, individuals experienced rapid and profound reductions in bone stiffness and bone mineral at the knee. FE models predicted similar reductions to axial and torsional stiffness, suggesting that both failure modes may be clinically relevant. Importantly, CT-derived measures of bone mineral alone underpredicted the impacts of SCI, compared to FE-derived measures of stiffness. TRIAL REGISTRATION:ClinicalTrials.gov (NCT01225055, NCT02325414).

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Morphologic features of the distal femur and tibia plateau in Southeastern Chinese population: A cross-sectional study.

Publications

Morphologic features of the distal femur and tibia plateau in Southeastern Chinese population: A cross-sectional study.

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