Ontology highlight
ABSTRACT:
SUBMITTER: Ribaucourt A
PROVIDER: S-EPMC5725683 | biostudies-other | 2017 Nov
REPOSITORIES: biostudies-other
Chemistry (Weinheim an der Bergstrasse, Germany) 20171030 65
A ring-closing alkene metathesis (RCM)/ oxyselenation-selenoxide elimination sequence was established to the sodium salts E- and Z-25 of the originally proposed structure for the recently isolated cytotoxin aruncin B (1), as well as to the sodium salt Z-34 of a related ethyl ether regioisomer; however, none of their corresponding free acids could be obtained. Their acid sensitivity, together with detailed analysis of the spectroscopic data indicated that profound structural revision was necessar ...[more]